Annals of Burns and Fire Disasters - vol. IX - n. 3 - September
1996
HYDROELECTROLYTIC DISTURBANCES IN BURN PATIENTS DURING
THE EMERGENCY PERIOD AND THEIR TREATMENT
Dauti L, Andrea A., Osman X.H.
Hospital 2, Department of Burns and Plastic
Surgery, Tirana, Albania
SUMMARY. This
paper considers the nature of burn shock, which is the main cause of mortality unless
local and systemic treatment is correctly administered. The primary and secondary
manifestations are described. The effects of burn shock are described in relation to 75
burn patients. Sodium plasma concentrations were significantly reduced, while potassium
plasma levels rose considerably in 29 patients. An increase in glycaemia was seen in 28
cases; 29 cases presented haemoglobinuria and bilirubinuria due to haernolysis. Serious
complications were prevented by fluid replacement and the treatment of hydroelectrolytic
and metabolic disturbances. All the patients who died were suffering from critical burns
and were admitted to the Burns Department after a considerable delay.
Introduction
Burn shock is the first consequence of
deep and extensive burns and constitutes the main cause of mortality if local and systemic
treatments are not correct and timely.
Burn shock - a type of hypovolaemic shock - in the first stages is dominated by
disturbances in membrane permeability accompanied by oedema, exudation and evaporation.
Secondary manifestations of these processes include plasma loss, haemoconcentration,
increased blood viscosity and all the haemodynamic consequences that these imply. Without
intensive therapy, circulatory shock will follow.
Materials and method
Bum shock was observed in our patients
with intermediate and full-thickness burn involving 15% BSA (and less than 15 % in
patients aged over 65 or under IS years).
During the study period, 75 patients were treated in our Burn Center (8% of all patients);
the main cause of death was burn shock. Burn shock usually appeared within the first 2-12
hours after the thermal trauma and always before 24-36 hours. In these last cases the
patients were admitted to the hospital after some delay.
In critical burns, disturbances in membrane permeability in the burn area may result in
secondary disturbances in various organs, as a result of reduced perfusion and consequent
hypoxia.
The loss of fluid and protein, particularly alburnins, causes a decrease in
oncotic-osmotic pressure.
Determination of sodium and potassium in plasma after severe burn injuries showed a
significant drop in sodium concentration; potassium levels rose markedly in 29 cases,
while hyponatraemia with normal levels of potassium was observed in 6 cases.
In 28 cases an increase in glycaemia was observed. This was the consequence of the
disturbances of glucose metabolism and the increase of glycogen secretion in the pancreas
B cells of pancreas. We believe that ketacholamines could be high, but we were unable to
determine this.
In 29 cases, haemoglobinuria and bilimbinuria were observed. These were caused by
haemolysis.
The correct and rational treatment of burn shock, fluid replacement, and the treatment of
hydroelectrolytic and metabolic disturbances improve the function of the visceral organs
and prepare the patient for surgery. This treatment prevents the occurrence of serious
life-threatening complications. All such procedures have to be carried out as soon as
possible.
In our study all the patients who died
were patients with critical burns who were not admitted in good time (Table 1).
Delay of hospitalization after trauma (hours) |
N' cases |
% |
2 |
16 |
21.4 |
8 |
36 |
48.0 |
12 |
18 |
24.0 |
24 |
5 |
6.6 |
|
Table 1 - Number of patients with burn shock in
relation to time of hospitalization in our Burn Centre |
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The treatment of
burn patients with burn shock was based on the Baxter/Parkland formula: 4 m] x body weight
x % burned BSA (half administered in the first 8 hours and the remaining half in the
following 16 hours).
Infusion therapy consisted of lactated Ringer's solution and sodium bicarbonate. Valium
was given for pain relief; Phenergan and pethidine were also used. Vitamin C was
administered 1-1.5 gr/day as the enzymatic regulator of cellular processes. Oxygen therapy
was used in all cases.
Discussion
The hydroelectrolytic disturbances
occurring after injuries are responsible for conditions that favour the development of
burn shock.
Disturbances in membrane permeability are accompanied by oedema, plasma loss,
haemoconcentration, increased blood viscosity, and hypomobility of circulating plasma.
Hypo-oedema and haemoconcentration reduce capillary perfusion, which can lead to organ
damage. Hypoxia blocks the Krex cycle, and there is consequently an interruption of
glucose metabolism and the onset of metabolic acidosis. These disturbances may lead to
cell disturbances in the burn area and the main organs. The most serious complication is
acute post-burn pulmonary distress, in which case the prognosis is reserved.
Conclusions
Critical burns are frequently
accompanied by hypovolaemic shock.
The time of hospitalization of patients
with critical burns is very important in relation to the treatment of burn shock and
prognosis.
Early treatment of burn shock decreases
mortality.
RESUME. Cet article
considère la condition de choc causée par les brûlures, qui est la cause principale de
la mort si le traitement local et systémique n'est pas correct. Les Auteurs, après avoir
considéré les manifestations primaires et secondaires du choc, présentent les
résultats de leurs observations de 75 patients brûlés. Les concentrations plasmatiques
de sodium étaient réduites en manière significative, tandis que les niveaux
plasmatiques de potassium étaient élevés dans 29 patients. La glycémie était élevée
dans 28 cas, et 29 cas présentaient l'hémoglobinurie et la bilirubinurie à cause de
l'hémolyse. Les complications graves peuvent être évitées par le remplacement des
fluides et le traitement des problèmes hydroelectrolytiques et métaboliques. Les
patients décédés, tous atteints de brûlures critiques, ont été hospitalisés dans le
Centre de Brûlés avec un fort délai.
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This paper was
received on 1 June 1995.
Address correspondence to: Dr 1.
Dauti, Hospital 2, Department of Burns and Plastic Surgery, Tirana, Albania. |
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